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TUESDAY, Jan. 20 (HealthDay News) Genetic testing isn't cost effective in guiding initial dosing of the blood thinner warfarin in patients with atrial fibrillation (a type of abnormal heart rhythm), a University of Cincinnati study finds.
costs less than $200.
They found that genotype guided dosing did result in better patient outcomes but at a cost of more Girls Nike Shoes 2017 than $170,000 per quality adjusted life year gained. They also found that there is only a 10 percent chance that genotype guided dosing is likely to be cost effective. The findings were published in the Jan. 20 issue of the journal Annals of Internal Medicine.
He and his colleagues analyzed the findings of three published studies and then created a model to estimate the cost effectiveness of genetic testing.
Benefit of Gene Tests Before Warfarin Rx
prevents more than 32 percent of major bleeding events;
is used for patients at high risk for hemorrhage;
during the initiation phase of warfarin dosing, which is the first month or so."
cost and treatment delays.
Warfarin is used to prevent blood clotting in these patients. Food and Drug Administration changed the labeling for warfarin to suggest that doctors consider genetic testing before using the blood thinner.
The researchers concluded that genotype guiding dosing is cost effective if it:
"The idea behind genetic testing also known as pharmacogenetic guided dosing is to help guide the initial, Nike Shoes Tumblr Girls
is available within 24 hours;
"This could be accomplished if testing were done in house, at lower cost and without delays," said Eckman. Currently, most of these tests have to be sent to outside laboratories, which can lead to increased Shoes Nike 2018
and possibly lower, dose of warfarin for patients," Eckman said. "The hope is that more accurate dosing will translate into decreased major bleeds Nike Shoes Red 2018
"There are certain genes that are known to contribute to an increased sensitivity to warfarin," study lead investigator Dr. Mark Eckman, professor of medicine, explained in a UC news release.
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